Cenforce 130 mg works by inhibiting the PDE5 enzyme in the body. This enzyme typically breaks down cyclic guanosine monophosphate (cGMP), a molecule that is responsible for relaxing the smooth muscles and blood vessels in the penis. When this enzyme is inhibited, cGMP levels increase, leading to the relaxation of blood vessels and a greater flow of blood to the penis. This process helps men achieve and maintain an erection during sexual arousal.